Before retrieval you can improve the query itself: Rewriting — resolve pronouns / context from chat history Expansion — add synonyms / related terms (map "cancer gene" to BRCA1/2, TP53) HyDE — generate a hypothetical answer and embed that Decomposition — split a multi-part question into sub-queries, retrieve for each In genomics, expanding a lay question into the technical terms present in the report is high-value, because patients and reports use different vocabularies.